Gordon Syndrome


Gordon Syndrome is a very rare genetic disorder that affects the joints of the ankle, knees, elbows, and wrists. The stricken joints are permanently flexed or contracted, which leads to reduced mobility and stiffness in the distal extremities.

As a genetic disorder (a mutation in the PIEZO2 gene), Gordon syndrome is typically diagnosed at birth where it may be observed in deformities including clubfoot, permanent flexure of several fingers, curvature of the spine, cleft palate and other birth defects. However, there is a wide variability in the expression and severity of this syndrome, and treatment or therapy is symptom-specific. For cases of clubfoot related to Gordon syndrome, a podiatric surgeon can perform corrective surgery to improve mobility and reduce the risk of other complications.

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Houston Foot and Ankle Care
2900 Weslayan, Suite 650
Houston, TX 77027
Phone: 281-612-4732
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