Jackson-Weiss Syndrome (JS) is a genetic disorder (a mutation of the FGFR2 gene) that triggers overstimulated bone cell growth. This abnormal bone development leads to premature fusion of the skull bones, preventing further growth and affecting the overall shape fo the head and facial features.
JWS also causes foot deformities, most commonly affecting the toes. Though the severity of symptoms may vary among patients, common traits are fused toe bones, large and stubby big toes, and the appearance of webbed skin between the second and third toes. A podiatrist can evaluate such symptoms and recommend corrective surgery as necessary.